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1. #GRAPEFRUIT SEED EXTRACT BENEFITS FOR SINUS PLUS#
2. #GRAPEFRUIT SEED EXTRACT BENEFITS FOR SINUS SERIES#

As of October 3, 2020, COVID-19 has infected over 34,790,000 and caused over 1,031,000 deaths worldwide. COVID-19 has caused a significant impact on the healthcare systems of various countries across the globe. In contrast, a moderate disease in high-risk patients and patients with severe conditions generally require hospitalization . Currently, the management and therapeutic options for COVID-19 are limited, including self-quarantine and supportive care, usually indicated for mild cases. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel virus and the causative agent of the Coronavirus disease 2019 (COVID-19).

#GRAPEFRUIT SEED EXTRACT BENEFITS FOR SINUS PLUS#

Xlear nasal spray, containing xylitol plus GSE, given its established safety profile and compelling clinical results described here, could be a potential adjunct treatment option in mild-moderate COVID-19 cases. No safety issues were noted during the course of treatment.

#GRAPEFRUIT SEED EXTRACT BENEFITS FOR SINUS SERIES#

We present a series of three mild-moderate risks, symptomatic, COVID-19 patients, treated with the intranasal combination, as an adjuvant to their ongoing treatment, with rapid clinical improvement and shorten time to negativization on repeat intranasal swab test via PCR. With a well-established safety profile, the components of this nasal spray have been studied and have been shown to have potential efficacy against viral pathogens, including coronavirus, and may potentially regulate pathways important in the initial entry of infection, replication, and systemic response to SARS-CoV-2. Hence, we postulated that re-purposing a commercially available nasal spray containing xylitol and grapefruit seed extract (GSE), namely Xlear Nasal Spray® (Xlear, Inc., American Fork, USA) could be used as an adjunct treatment of COVID-19. Having a mode of transmission as a droplet mode, several studies have supported how the nose can contain the primary route of entry of SARS-CoV-2. Re-purposing already established medications, with excellent safety profiles, is a possible approach for treating the disease in its early stage. While several studies have suggested different treatment modalities, there is still no definitive treatment against COVID-19. During the early stages of the disease, treatment is mainly supportive. Being a novel virus, several treatments have been explored against COVID-19. (Polyphenols are substances that are found in many plants and have antioxidant activity.) This research is also looking at how the microbiome affects the absorption of the specific polyphenol components that are helpful.The SARS-CoV-2 virus has created an unprecedented impact on healthcare globally.

The National Center for Complementary and Integrative Health (NCCIH) is supporting research on how certain dietary supplements rich in polyphenols, including grape seed extract, help to reduce the effects of stress on the body and mind.The individual studies, however, were small in size, which could affect the interpretation of the results. A 2019 review of 15 studies involving 825 participants suggested that grape seed extract might help lower levels of LDL cholesterol, total cholesterol, triglycerides, and the inflammatory marker C-reactive protein.But people with high blood pressure should not take high doses of grape seed extract with vitamin C because the combination might worsen blood pressure. It’s possible that grape seed extract might help to slightly lower blood pressure in healthy people and those with high blood pressure, particularly in people who are obese or have metabolic syndrome.